Brief Information of the Compound and Protein
Compound Name
trans-1-[[3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]cyclobutyl]methyl]-3-[3-(hydroxymethyl)tetrahydrofuran-3-yl]urea
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Canonical SMILES
O=C(NC[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1)NC1(CO)CCOC1
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Compound Formula C25H26F3N3O3
Compound Structure
Protein Name
Apolipoprotein L1
Protein Classification
Unclassified protein
Uniprot ID
O14791
Gene Name
APOL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS