Brief Information of the Compound and Protein
Compound Name
trans-3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-N-(2-hydroxyethyl)cyclobutanecarboxamide
    Show/Hide
Canonical SMILES
O=C(NCCO)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1
    Show/Hide
Compound Formula C21H19F3N2O2
Compound Structure
Protein Name
Apolipoprotein L1
Protein Classification
Unclassified protein
Uniprot ID
O14791
Gene Name
APOL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  1
1
IC50 < 250 nM
   TI
   LI
   LO
   TS