Brief Information of the Compound and Protein
Compound Name
trans-3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-N-(5-methylisoxazol-3-yl)cyclobutanecarboxamide
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Canonical SMILES
Cc1cc(NC(=O)[C@H]2C[C@H](c3c(-c4ccc(F)cc4)[nH]c4c(F)cc(F)cc43)C2)no1
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Compound Formula C23H18F3N3O2
Compound Structure
Protein Name
Apolipoprotein L1
Protein Classification
Unclassified protein
Uniprot ID
O14791
Gene Name
APOL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  1
1
IC50 = 0.25 nM
   TI
   LI
   LO
   TS