Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CPI-444
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 PubChem ID
CID: 44537963
SID: 87219378
Canonical SMILES
Cc1ccc(o1)-c1nc(N)nc2n(Cc3cccc(CO[C@H]4CCOC4)n3)nnc12
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Compound Formula C20H21N7O3
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A2a
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P29274
Gene Name
ADORA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 86.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 3353 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 10000 nM