Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-ethynylnaphthalen-1-yl)-8-fluoro-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethoxy)pyrido[4,3-d]pyrimidine
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 PubChem ID
CID: 164521255
Canonical SMILES
Fc1c(ncc2c(nc(OCC34CCCN3CCC4)nc12)N1C[C@@H]2CC[C@H](C1)N2)-c1cccc2cccc(C#C)c12
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Compound Formula C33H33FN6O
Compound Structure
Protein Name
 Protein Info 
GTPase KRas
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P01116
Gene Name
KRAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 71 nM
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