Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-ylmethoxy)pyrido[4,3-d]pyrimidin-7-yl]-5-ethynylnaphthalen-2-ol
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 PubChem ID
CID: 163322337
Canonical SMILES
Oc1cc(-c2ncc3c(nc(OCC45CCCN4CCC5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(cccc2c1)C#C
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Compound Formula C33H33FN6O2
Compound Structure
Protein Name
 Protein Info 
GTPase KRas
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P01116
Gene Name
KRAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 14 nM
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