Brief Information of the Compound and Protein
Compound Name
4-[4-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]naphthalen-2-ol
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PubChem ID
CID: 156117314
Canonical SMILES
CN1CCC[C@H]1COc1nc(N2C[C@@H]3CC[C@H](C2)N3)c2cnc(c(F)c2n1)-c1cc(O)cc2ccccc12
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Compound Formula C29H31FN6O2
Compound Structure
Protein Name
GTPase KRas
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P01116
Gene Name
KRAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS Homo sapiens (Human)  1
1
IC50 = 530 nM
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