Brief Information of the Compound and Protein
Compound Name
5-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
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PubChem ID
CID: 166630169
Canonical SMILES
CNc1nc(Nc2ccc(nc2)C(N)=O)ncc1C(F)(F)F
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Compound Formula C12H11F3N6O
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 186.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 190.3 nM
   TI
   LI
   LO
   TS