Brief Information of the Compound and Protein
Compound Name
6-ethyl-3-[3-methoxy-4-(4-piperazin-1-ylpiperidin-1-yl)anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
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PubChem ID
CID: 166626288
Canonical SMILES
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCNCC3)c(OC)c2)nc1NC1CCOCC1
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Compound Formula C28H42N8O3
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 6.25 nM
   TI
   LI
   LO
   TS
2
IC50 = 12.98 nM
   TI
   LI
   LO
   TS