Brief Information of the Compound and Protein
Compound Name
 Compound Info 
dimethyl 5-(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)benzene-1,3-dicarboxylate
    Show/Hide
 PubChem ID
CID: 5112652
Canonical SMILES
COC(=O)c1cc(NC(=O)c2cnn3cccnc23)cc(c1)C(=O)OC
    Show/Hide
Compound Formula C17H14N4O5
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3700 nM
   TI
   LI
   LO
   TS
CL000494 THP1-Dual
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3500 nM
   TI
   LI
   LO
   TS
CL000585 THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 100000 nM
2 IC50 > 100000 nM