Brief Information of the Compound and Protein
Compound Name
2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
    Show/Hide
Canonical SMILES
OC(=O)c1cccc2cc(CNC(=O)c3cnn4cccnc34)oc12
    Show/Hide
Compound Formula C17H12N4O4
Compound Structure
Protein Name
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000494 THP1-Dual Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000585 THP1-Dual KO-STING Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 50000 nM
2 EC50 = 71000 nM
3 IC50 = 14000 nM
4 IC50 = 40000 nM