Brief Information of the Compound and Protein
Compound Name
N-[[5-chloro-7-(2H-tetrazol-5-yl)-1-benzofuran-2-yl]methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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PubChem ID
CID: 164866489
Canonical SMILES
Clc1cc(-c2nn[nH]n2)c2oc(CNC(=O)c3cnn4cccnc34)cc2c1
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Compound Formula C17H11ClN8O2
Compound Structure
Protein Name
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  1
1
EC50 = 96000 nM
   TI
   LI
   LO
   TS
CL000494 THP1-Dual Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000585 THP1-Dual KO-STING Homo sapiens (Human)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 5900 nM
2 EC50 = 38000 nM
3 IC50 = 1700 nM
4 IC50 = 15000 nM