Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-butoxy-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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Canonical SMILES
CCCCOc1cc(C(=O)Nc2cc(cc(c2)C(F)(F)F)-n2cnc(C)c2)c2ccccc2n1
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Compound Formula C25H23F3N4O2
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor subfamily 2 group E member 1
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 2
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Nuclear hormone receptor subfamily 2 group E
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Nuclear hormone receptor subfamily 2 group E member 1
Uniprot ID
Q9Y466
Gene Name
NR2E1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 5000 nM
2 Kd = 1600 nM