Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(2,9-dimethyl-8-oxo-6-thia-2,9,12,14-tetrazatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-13-yl)amino]benzenesulfonamide
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 PubChem ID
CID: 121499143
Canonical SMILES
CN1c2ccsc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12
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Compound Formula C17H16N6O3S2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase MST subfamily
Uniprot ID
Q13043
Gene Name
STK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1040 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 104 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.8 nM
2 Kd = 17 nM