Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEMBL5081453
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 PubChem ID
CID: 166627329
Canonical SMILES
CN(C)C(=O)c1c(N)ccc(c1F)-c1cnc2NC[C@@]3(CC[C@]4(C3)CCCCNC4=O)c2c1Cl
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Compound Formula C25H29ClFN5O2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase KHS subfamily
Uniprot ID
Q92918
Gene Name
MAP4K1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.2 nM