Brief Information of the Compound and Protein
Compound Name
1-(6,7-Dichloro-9b-(4,6-difluoro-1H-indol-3-yl)-1,3,4,9b-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one
    Show/Hide
PubChem ID
CID: 166633056
Canonical SMILES
O=C(CO)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(c2c[nH]c3cc(F)cc(F)c23)C1
    Show/Hide
Compound Formula C21H15Cl2F2N3O2
Compound Structure
Protein Name
Cyclic GMP-AMP synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8N884
Gene Name
CGAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000494 THP1-Dual Homo sapiens (Human)  1
1
IC50 = 12900 nM
   TI
   LI
   LO
   TS