Brief Information of the Compound and Protein
Compound Name
1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-(propan-2-ylamino)-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone
    Show/Hide
PubChem ID
CID: 166635525
Canonical SMILES
CC(C)Nc1nc2CN(C=Cc2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(C)=O
    Show/Hide
Compound Formula C23H27F2N5O2
Compound Structure
Protein Name
G-protein coupled receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Uniprot ID
P46095
Gene Name
GPR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 34000 nM
   TI
   LI
   LO
   TS
CL000308 T-REx-CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 16 nM
   TI
   LI
   LO
   TS