Brief Information of the Compound and Protein
Compound Name
N-cyclopropyl-3-[4-[(2,4-difluorophenyl)methyl]piperazin-1-yl]pyrido[3,4-b]pyrazin-2-amine
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PubChem ID
CID: 118308612
Canonical SMILES
Fc1ccc(CN2CCN(CC2)c2nc3cnccc3nc2NC2CC2)c(F)c1
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Compound Formula C21H22F2N6
Compound Structure
Protein Name
G-protein coupled receptor 6
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
P46095
Gene Name
GPR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 39000 nM
   TI
   LI
   LO
   TS
CL000308 T-REx-CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 7 nM
   TI
   LI
   LO
   TS