Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-[(1R,6R,8R,9R,10R,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-difluoro-3-hydroxy-12-oxo-12-sulfanyl-3-sulfanylidene-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]purin-6-amine
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Canonical SMILES
Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2CO[P@](S)(=O)O[C@@H]3[C@@H](CO[P@@](S)(=O)O[C@H]2[C@H]1F)O[C@H]([C@@H]3F)n1cnc2c(N)ncnc12
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Compound Formula C20H22F2N10O8P2S2
Compound Structure
Protein Name
 Protein Info 
Stimulator of interferon genes protein
Protein Classification
Unclassified protein
Uniprot ID
Q86WV6
Gene Name
STING1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
2
EC50 = 520 nM
   TI
   LI
   LO
   TS
CL000494 THP1-Dual
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 310 nM
   TI
   LI
   LO
   TS
2
EC50 = 3030 nM
   TI
   LI
   LO
   TS