Brief Information of the Compound and Protein
Compound Name
2-[[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl]-1-methylimidazo[4,5-b]pyridine
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PubChem ID
CID: 166634449
Canonical SMILES
Cn1c(CN2CCN(CC2)c2ncc(cc2Cl)C(F)(F)F)nc2ncccc12
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Compound Formula C18H18ClF3N6
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
EC50 = 79 nM
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