Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(3-chloro-2-fluorophenyl)(3-(4-(3-(dimethylamino)azetidin-1-yl)-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylamino)pyrrolidin-1-yl)methanone
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 PubChem ID
CID: 166629225
Canonical SMILES
Cc1cc(Nc2cc(N3CC(N(C)C)C3)nc(N[C@H]3CCN(C(=O)c4cccc(Cl)c4F)C3)n2)n[nH]1
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Compound Formula C24H29ClFN9O
Compound Structure
Protein Name
 Protein Info 
Aurora kinase A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
O14965
Gene Name
AURKA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 29.8 nM
   TI
   LI
   LO
   TS