Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-N2-(1-(4-chloro-2-fluorophenylsulfonyl)pyrrolidin-3-yl)-6-(4-ethylpiperazin-1-yl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
    Show/Hide
Canonical SMILES
CCN1CCN(c2cc(Nc3cc(C)[nH]n3)nc(N[C@H]3CCN(S(=O)(=O)c4ccc(Cl)cc4F)C3)n2)CC1
    Show/Hide
Compound Formula C24H31ClFN9O2S
Compound Structure
Protein Name
 Protein Info 
Aurora kinase A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase AUR family
Uniprot ID
O14965
Gene Name
AURKA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 100 nM
   TI
   LI
   LO
   TS