Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4,5-dichlorothiophen-2-yl)sulfonyl-3-[(2E)-2-[1-(6-methoxypyridin-3-yl)-5,6-dihydro-4H-indazol-7-ylidene]ethyl]urea
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 PubChem ID
CID: 146293794
Canonical SMILES
COc1ccc(cn1)-n1ncc2CCC\C(=C/CNC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)c12
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Compound Formula C20H19Cl2N5O4S2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2 nM