Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(2E)-2-[1-[(2,4-dichlorophenyl)methyl]-5,6-dihydro-4H-indazol-7-ylidene]ethyl]-3-[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]urea
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 PubChem ID
CID: 146291666
Canonical SMILES
Cc1nc(C)c(s1)S(=O)(=O)NC(=O)NC\C=C1/CCCc2cnn(Cc3ccc(Cl)cc3Cl)c12
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Compound Formula C22H23Cl2N5O3S2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2 nM