Brief Information of the Compound and Protein
Compound Name
7-(1-but-2-ynoylpiperidin-4-yl)-2-[4-(2-methoxyphenoxy)phenyl]-5H-imidazo[1,2-b]pyrazole-3-carboxamide
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Canonical SMILES
COc1ccccc1Oc1ccc(cc1)-c1[nH]c2c(cnn2c1C(N)=O)C1CCN(CC1)C(=O)C#CC
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Compound Formula C28H27N5O4
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 62.5 nM
   TI
   LI
   LO
   TS