Brief Information of the Compound and Protein
Compound Name
2-(4-phenoxyphenyl)-7-(1-prop-2-ynoylpiperidin-4-yl)-5H-imidazo[1,2-b]pyrazole-3-carboxamide
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Canonical SMILES
NC(=O)c1c([nH]c2c(cnn12)C1CCN(CC1)C(=O)C#C)-c1ccc(Oc2ccccc2)cc1
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Compound Formula C26H23N5O3
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 7.6 nM
   TI
   LI
   LO
   TS