Brief Information of the Compound and Protein
Compound Name
7-(1-but-2-ynoylazetidin-3-yl)-2-[4-(4-methoxyphenoxy)phenyl]-5H-imidazo[1,2-b]pyrazole-3-carboxamide
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Canonical SMILES
COc1ccc(Oc2ccc(cc2)-c2[nH]c3c(cnn3c2C(N)=O)C2CN(C2)C(=O)C#CC)cc1
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Compound Formula C26H23N5O4
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 153 nM
   TI
   LI
   LO
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