Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[6-[(2-hydroxy-2-methylpropyl)amino]pyrimidin-4-yl]oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
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Canonical SMILES
CC(C)(O)CNc1cc(Oc2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)cc2)ncn1
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Compound Formula C22H22F3N5O3
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase TNNI3K
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase MLK family
>
TKL protein kinase HH498 subfamily
Uniprot ID
Q59H18
Gene Name
TNNI3K
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001016 HEKMSR2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM