Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-chloro-5-ethyl-4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
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 PubChem ID
CID: 50995158
SID: 117641319
Canonical SMILES
CCc1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc(Cl)c1Oc1cc(NC)ncn1
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Compound Formula C21H19ClF3N5O2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase TNNI3K
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase MLK family
>
TKL protein kinase HH498 subfamily
Uniprot ID
Q59H18
Gene Name
TNNI3K
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001016 HEKMSR2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 <= 10 nM