Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-amino-5-[4-[[4-(4-chlorophenyl)pyridin-2-yl]carbamoyl]phenyl]-2-[(2S)-1-prop-2-enoylpiperidin-2-yl]imidazole-4-carboxamide
    Show/Hide
 PubChem ID
CID: 155307326
Canonical SMILES
NC(=O)c1c(nc([C@@H]2CCCCN2C(=O)C=C)n1N)-c1ccc(cc1)C(=O)Nc1cc(ccn1)-c1ccc(Cl)cc1
    Show/Hide
Compound Formula C30H28ClN7O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase ITK/TSK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q08881
Gene Name
ITK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1915 nM
   TI
   LI
   LO
   TS