Brief Information of the Compound and Protein
Compound Name
N-[5-[[3,5-bis(trifluoromethyl)phenyl]methyl]-6,6-dimethyl-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide
    Show/Hide
Canonical SMILES
CC1(C)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)Cc2c(NC(=O)c3ccccc3)n[nH]c12
    Show/Hide
Compound Formula C23H20F6N4O
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 16360 nM
   TI
   LI
   LO
   TS