Brief Information of the Compound and Protein
Compound Name
3-[[4-(2-methoxyphenyl)-2,5-dioxopyrrol-3-yl]amino]benzonitrile
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Canonical SMILES
COc1ccccc1C1=C(Nc2cccc(c2)C#N)C(=O)NC1=O
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Compound Formula C18H13N3O3
Compound Structure
Protein Name
STE20-like serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
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STE protein kinase STE20 family
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STE protein kinase SLK subfamily
Uniprot ID
Q9H2G2
Gene Name
SLK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.2 nM
2 Ki = 3.7 nM