Brief Information of the Compound and Protein
Compound Name
3-[1-(azetidin-3-yl)pyrazol-4-yl]-7-[3,5-dimethoxy-N-[2-(propan-2-ylamino)ethyl]anilino]pyrido[1,2-a]pyrimidin-4-one
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Canonical SMILES
COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(-c3cnn(c3)C3CNC3)c(=O)n2c1
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Compound Formula C27H33N7O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS