Brief Information of the Compound and Protein
Compound Name
3-(3-(1-(1-ethoxyethyl)-1H-pyrazol-4-yl)phenyl)-5-(4-isopropyl-4H-1,2,4-triazol-3-yl)-1H-indazole
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Canonical SMILES
CCOC(C)n1cc(-c2cccc(-c3n[nH]c4ccc(-c5nncn5C(C)C)cc34)c2)cn1
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Compound Formula C25H27N7O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 5
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE11 family
Uniprot ID
Q99683
Gene Name
MAP3K5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 4462 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 29.9 nM