Brief Information of the Compound and Protein
Compound Name
3-[3-(4-cyclopropylimidazol-1-yl)-5-methoxyphenyl]-5-(4-propan-2-yl-1,2,4-triazol-3-yl)-1H-indazole
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Canonical SMILES
COc1cc(cc(c1)-n1cnc(c1)C1CC1)-c1n[nH]c2ccc(cc12)-c1nncn1C(C)C
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Compound Formula C25H25N7O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 5
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE11 family
Uniprot ID
Q99683
Gene Name
MAP3K5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 11294 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 48.6 nM