Brief Information of the Compound and Protein
Compound Name
5-[(2R)-11-(4-amino-4-methylpiperidin-1-yl)-4,7,10-triazatricyclo[7.4.0.02,7]trideca-1(9),10,12-trien-4-yl]quinoline-8-carbonitrile
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PubChem ID
CID: 156388181
Canonical SMILES
CC1(N)CCN(CC1)c1ccc2[C@@H]3CN(CCN3Cc2n1)c1ccc(C#N)c2ncccc12
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Compound Formula C26H29N7
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000686 HEK-Blue hTLR7 Homo sapiens (Human)  1
1
IC50 = 8.7 nM
   TI
   LI
   LO
   TS