Brief Information of the Compound and Protein
Compound Name
6-bromo-2,8-dioxo-3-(2H-tetrazol-5-yl)pyrano[2,3-f]chromene-9-carboxylic acid
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PubChem ID
CID: 154634326
Canonical SMILES
OC(=O)c1cc2c(oc1=O)c(Br)cc1cc(-c3nnn[nH]3)c(=O)oc21
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Compound Formula C14H5BrN4O6
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 25.92 nM
   TI
   LI
   LO
   TS
2
IC50 = 15.9 nM
   TI
   LI
   LO
   TS
CL000007 HT-29 Homo sapiens (Human)  3
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
2
IC50 = 18 nM
   TI
   LI
   LO
   TS
3
IC50 = 830 nM
   TI
   LI
   LO
   TS