Brief Information of the Compound and Protein
Compound Name
6-(4-methoxyphenyl)-2,8-dioxopyrano[2,3-f]chromene-3,9-dicarboxylic acid
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PubChem ID
CID: 154634332
Canonical SMILES
COc1ccc(cc1)-c1cc2cc(C(O)=O)c(=O)oc2c2cc(C(O)=O)c(=O)oc12
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Compound Formula C21H12O9
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 6.93 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.45 nM
   TI
   LI
   LO
   TS
CL000007 HT-29 Homo sapiens (Human)  3
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 7 nM
   TI
   LI
   LO
   TS
3
IC50 = 470 nM
   TI
   LI
   LO
   TS