Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4,17-dioxo-3,18-dioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8,10,12,15-heptaene-5,16-dicarboxylic acid
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 PubChem ID
CID: 154634333
Canonical SMILES
OC(=O)c1cc2c3ccccc3c3cc(C(O)=O)c(=O)oc3c2oc1=O
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Compound Formula C18H8O8
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.31 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.47 nM
   TI
   LI
   LO
   TS
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS
3
IC50 = 460 nM
   TI
   LI
   LO
   TS