Brief Information of the Compound and Protein
Compound Name
10-(4-methoxyphenyl)-2,8-dioxopyrano[3,2-g]chromene-3,7-dicarboxylic acid
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PubChem ID
CID: 154634321
Canonical SMILES
COc1ccc(cc1)-c1c2oc(=O)c(cc2cc2cc(C(O)=O)c(=O)oc12)C(O)=O
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Compound Formula C21H12O9
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 62.83 nM
   TI
   LI
   LO
   TS
2
IC50 = 48.15 nM
   TI
   LI
   LO
   TS
CL000007 HT-29 Homo sapiens (Human)  3
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 2 nM
   TI
   LI
   LO
   TS
3
IC50 = 180 nM
   TI
   LI
   LO
   TS