Brief Information of the Compound and Protein
Compound Name
10-methyl-4,6-dioxo-1,9-dihydropyrido[3,2-g]quinoline-2,8-dicarboxylic acid
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PubChem ID
CID: 326869
Canonical SMILES
Cc1c2[nH]c(cc(=O)c2cc2c1[nH]c(cc2=O)C(O)=O)C(O)=O
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Compound Formula C15H10N2O6
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1.08 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.74 nM
   TI
   LI
   LO
   TS
CL000007 HT-29 Homo sapiens (Human)  3
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 2 nM
   TI
   LI
   LO
   TS
3
IC50 = 789 nM
   TI
   LI
   LO
   TS