Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4,6-dimethoxy-10-methylpyrido[3,2-g]quinoline-2,8-dicarboxylic acid
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Canonical SMILES
COc1cc(nc2c(C)c3nc(cc(OC)c3cc12)C(O)=O)C(O)=O
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Compound Formula C17H14N2O6
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 8.13 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.11 nM
   TI
   LI
   LO
   TS
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
2
IC50 = 65 nM
   TI
   LI
   LO
   TS
3
IC50 = 282 nM
   TI
   LI
   LO
   TS