Brief Information of the Compound and Protein
Compound Name
(1R)-1-[6-(2-cyclopropylphenyl)pyridin-2-yl]-2,2-difluoro-6-azaspiro[2.5]octane-6-sulfonamide
    Show/Hide
Canonical SMILES
NS(=O)(=O)N1CCC2(CC1)[C@H](c1cccc(n1)-c1ccccc1C1CC1)C2(F)F
    Show/Hide
Compound Formula C21H23F2N3O2S
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Nicotinic acetylcholine receptor
>
Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 830 nM
   TI
   LI
   LO
   TS