Brief Information of the Compound and Protein
Compound Name
5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)-N-[(3S,4S,6S)-4-(3,4-difluorophenyl)-6-[2-(methylamino)-2-oxoethyl]piperidin-3-yl]furan-2-carboxamide
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PubChem ID
CID: 138911338
Canonical SMILES
CNC(=O)C[C@@H]1C[C@H]([C@@H](CN1)NC(=O)c1cc(c(Cl)o1)-c1c(Cl)cnn1C)c1ccc(F)c(F)c1
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Compound Formula C23H23Cl2F2N5O3
Compound Structure
Protein Name
RAC-beta serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31751
Gene Name
AKT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.2 nM