Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,6S)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-5,11-dioxo-19-oxa-4,10-diazatricyclo[18.2.2.06,10]tetracosa-1(23),20(24),21-triene-3-carboxamide
    Show/Hide
Canonical SMILES
C[C@@]1(CO1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccc(OCCCCCCCC(=O)N3CCC[C@H]3C(=O)N1)cc2
    Show/Hide
Compound Formula C34H43N3O6
Compound Structure
Protein Name
 Protein Info 
Proteasome subunit beta type-9
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1B subfamily
Uniprot ID
P28065
Gene Name
PSMB9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000186 RPMI-8226
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 32.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 105.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 184.1 nM