Brief Information of the Compound and Protein
Compound Name
2,2-Difluoro-3-((1R,3R)-1-(6-((1-(3-fluoropropyl)azetidin-3-yl)amino)pyridin-3-yl)-3-methyl-3,4-dihydro-1Hpyrido[3,4-b]indol-2(9H)-yl)propan-1-ol
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Canonical SMILES
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2ccc(NC3CN(CCCF)C3)nc2)N1CC(F)(F)CO
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Compound Formula C26H32F3N5O
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS