Brief Information of the Compound and Protein
Compound Name
6-methoxy-4-[4-[(3-propan-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperidin-1-yl]quinoline-3-carbonitrile
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Canonical SMILES
COc1ccc2ncc(C#N)c(N3CCC(Cc4nc(no4)C(C)C)CC3)c2c1
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Compound Formula C22H25N5O2
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  2
1
IC50 = 764 nM
   TI
   LI
   LO
   TS
2
IC50 = 9660 nM
   TI
   LI
   LO
   TS