Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[[7-[2-(azetidin-1-yl)-2-oxoethyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]oxy]-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
    Show/Hide
Canonical SMILES
CC(C)n1cc(C(=O)Nc2ccc(Oc3ncnc4CN(CC(=O)N5CCC5)CCc34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O
    Show/Hide
Compound Formula C32H31F2N7O5
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q00993
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 66 nM
   TI
   LI
   LO
   TS