Brief Information of the Compound and Protein
Compound Name
1-(2-fluoroethyl)-N-[3-fluoro-4-[[7-[(1-methylpiperidin-4-yl)methyl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]oxy]phenyl]-3-(4-fluorophenyl)-2,4-dioxopyrimidine-5-carboxamide
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Canonical SMILES
CN1CCC(CN2CCc3c(C2)ncnc3Oc2ccc(NC(=O)c3cn(CCF)c(=O)n(-c4ccc(F)cc4)c3=O)cc2F)CC1
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Compound Formula C33H34F3N7O4
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q00993
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 49 nM
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