Brief Information of the Compound and Protein
Compound Name
N-[3-fluoro-4-[[6-(oxan-4-ylmethyl)-5,7-dihydropyrrolo[3,4-d]pyrimidin-4-yl]oxy]phenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
    Show/Hide
Canonical SMILES
CC(C)n1cc(C(=O)Nc2ccc(Oc3ncnc4CN(CC5CCOCC5)Cc34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O
    Show/Hide
Compound Formula C32H32F2N6O5
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q00993
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS